Can I use these medications if I'm pregnant or breastfeeding?
These medications should not be used during pregnancy, as they may affect fetal development. If you're using oral contraceptive pills and taking these medications, you may need additional barrier contraception (such as condoms) or should switch to a non-oral method such as an IUD or implant.
If you miss a dose of your oral contraceptive pill or experience vomiting or diarrhoea, you should take a repeat dose of your pill. Contact your Family Physician / Nurse Practitioner or call 811 (Health Link Alberta) for medical advice if this occurs.
If you're planning to become pregnant, discuss this with your healthcare provider before starting treatment.
How do these medications interact with hormone replacement therapy?
Some people taking GLP-1 medications may notice changes in their vaginal bleeding, particularly if they're also using hormone replacement therapy (HRT). This can happen because GLP-1 medications slow down digestion, which can affect how your body absorbs hormone treatments - especially HRT taken as tablets.
There don't appear to be the same issues with hormone patches or intrauterine devices (such as the Mirena coil). Weight loss and other body changes may also play a role.
This kind of bleeding is usually not serious, but it's important to tell your doctor if you experience new, heavy, or ongoing bleeding. They can check for other causes and may suggest adjusting your HRT or carrying out further tests if needed.
Are there any medical conditions that would prevent me from taking these medications?
Your clinician will assess your complete medical history during the consultation to determine suitability. In the Consultation you should inform them of:
- History of thyroid cancer or multiple endocrine neoplasia (MEN)
- Pancreatitis or gallbladder disease
- Severe kidney or liver disease
- Any allergies to the medication or its components
- Current medications and supplements
- Pregnancy or plans to become pregnant